Preston will be tested over the next ten days starting with Colchester who will look to build on an impressive start to the season.
Liam Chilvers will face his old club for the first time partnering St Ledger at the back. Ormerod is set to start up front with Nugent and Simpson will be hoping for goals from his front pair going into the festive season.
Preston will hope to maintain their unbeaten home record and if they do so it will set them up nicely for two tricky ties at West Brom and Sunderland.